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. 2013 Jan 29;51(4):263–273. doi: 10.5414/CP201793

Table 2. Noncompartmental pharmacokinetic analysis results for 15 healthy subjects administered the MBT with and without Orlistat. tmax reported as the median and range.

Treatment Fat C0
(mg/dl)
tmax
(h)
Cmax
(mg/dl)
AUC
(mg×h×dl–1)
None HA Mean 0.979 5.5 11.2 36.4
SD 0.429 [4 – 7] 8.68 30.2
95% CI (0.741, 1.22) (6.38, 16.0) (19.7, 53.2)
PA Mean 0.763 4 6.19 25.1
SD 0.394 [2 – 6] 4.27 17.4
95% CI (0.545, 0.981) (3.83, 8.55) (15.5, 34.7)
Orlistat HA Mean 1.28 4.5 3.28 12.8
SD 0.340 [3 – 6] 2.44 8.54
95% CI (1.07, 1.39) (1.93, 4.64) (8.03, 17.5)
PA Mean 1.02 4 5.26 21.6
SD 0.674 [2 - 6] 3.14 11.8
95% CI (0.646, 1.39) (3.52, 6.99) (15.1, 28.1)