FIG. 2.
Phylogenetic tree based on nucleotide sequences of bovine IFN-α1 and type I IFN from different species by the neighbor-joining method. GenBank accession numbers are as follows: human IFNα1 (NM_024013), human IFNα2 (NM_000605), human IFNα6 (NM_021002), human IFNα7 (BC074992), murine IFNα1 (NM_010502), murine IFNα2 (NM_010503), murine IFNα4 (NM_010504), murine IFNα5 (NM_010505), porcine IFNα1 (DQ249000), porcine IFNα2 (DQ249002), porcine IFNα7 (DQ872660), porcine IFNα8 (DQ248999), bovine IFN-α1 (XP_001251758.1), bovine IFNαA (EU276064), bovine IFNαB (M10953), bovine IFNαC (NM_174085), bovine IFNαF (NM_001172042), bovine IFNαG (EU276064), horse IFNβ (NM_001172040), and sheep IFNβ (JX458084). The IFNβ of horse and sheep were selected as outgroups.