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. 2015 Feb 14;14:76. doi: 10.1186/s12936-015-0581-y

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© van der Velden et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Anti-malarial sensitivity assay of wild type and Pfmdr mutant parasites using seven drugs. Dose–response inhibition curves showing sensitivity of wild type (NF54), and P. falciparum mdr mutant (PfΔmdr2 and PfΔmdr5) parasites to ART (A), ATO (B), CQ (C), DHA (D), LUM (E), MQ (F) and QN (G) were plotted with fixed Hill slopes. All assays were repeated at least three times in triplicates in order to determine significant differences by a paired t-test between the obtained logIC₅₀-values of wild type and mutant groups.