Table 1. Established biomarkers in different grade astrocytomas.
Variables | NBT | AII | AIII | P value |
---|---|---|---|---|
PTEN mutation | NA | 5/140 (3.5%) |
3/17 (17.6%) |
<0.05 |
IDH1 mutation | NA | 131/182 (80%) |
13/33 (39.4%) |
<0.05 |
1p19q loss | 0/6 | 12/217 (5.5%) |
6/40 (15%) |
>0.05 |
TP53 mutation | NA | 67/149 (50.0%) |
5/18 (27.8%) |
<0.05 |
MGMT methylation | NA | 7/23 (30.4%) |
15/24 (62.5%) |
<0.05 |
EGFR amplification | 0/6 | 5/217 (2.3%) |
2/40 (5%) |
>0.05 |