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. 2014 Dec 31;5(24):12593–12606. doi: 10.18632/oncotarget.2518

Table 1. Established biomarkers in different grade astrocytomas.

Variables NBT AII AIII P value
PTEN mutation NA 5/140
(3.5%)
3/17
(17.6%)
<0.05
IDH1 mutation NA 131/182
(80%)
13/33
(39.4%)
<0.05
1p19q loss 0/6 12/217
(5.5%)
6/40
(15%)
>0.05
TP53 mutation NA 67/149
(50.0%)
5/18
(27.8%)
<0.05
MGMT methylation NA 7/23
(30.4%)
15/24
(62.5%)
<0.05
EGFR amplification 0/6 5/217
(2.3%)
2/40
(5%)
>0.05