Table 1. Currently available anticancer immunotherapies.
Paradigm | Licensed* |
---|---|
Tumor-targeting mAbs | YES |
Adoptive cell transfer | NO |
Oncolytic viruses | YES |
DC-based interventions | YES |
DNA-based vaccines | NO |
Peptide-based vaccines | YES |
Immunostimulatory cytokines | YES |
Immunomodulatory mAbs | YES |
Inhibitors of immunosuppressive metabolism | NO |
PRR agonists | YES |
ICD inducers | YES |
Others | YES |
Abbreviations. ICD, immunogenic cell death; DC, dendritic cell; mAb, monoclonal antibody; PRR, pattern recognition receptor.
in one of its forms for use in cancer patients, by the US Food and Drug Administration or equivalent regulatory agency worldwide.