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. 2014 Dec 18;5(24):12472–12508. doi: 10.18632/oncotarget.2998

Table 1. Currently available anticancer immunotherapies.

Paradigm Licensed*
Tumor-targeting mAbs YES
Adoptive cell transfer NO
Oncolytic viruses YES
DC-based interventions YES
DNA-based vaccines NO
Peptide-based vaccines YES
Immunostimulatory cytokines YES
Immunomodulatory mAbs YES
Inhibitors of immunosuppressive metabolism NO
PRR agonists YES
ICD inducers YES
Others YES

Abbreviations. ICD, immunogenic cell death; DC, dendritic cell; mAb, monoclonal antibody; PRR, pattern recognition receptor.

*

in one of its forms for use in cancer patients, by the US Food and Drug Administration or equivalent regulatory agency worldwide.