Table 3. Demographic and clinical measures associated with the length of abstinence during first 3 months of acamprosate treatment in the replication sample of 110 male alcoholics participating in study PREDICT.
| Parameter | Mean±s.d. | HR (95% CI) | P-value |
|---|---|---|---|
| Age at evaluation | 45.1±8.4 | 0.98 (0.95, 1.01) | 0.13 |
| Age of onset | 31.7±10.1 | 0.95 (0.95, 0.99) | 0.036 |
| Average drinks per heavy drinking day | 19.2±10.4 | 1.03 (1.01, 1.06) | 0.0087 |
| Average drinks per drinking day | 18.8±10.6 | 1.03 (1.01, 1.05) | 0.0084 |
| BDI score | 6.1±5.0 | 1.06 (1.01, 1.11) | 0.012 |
| OCDS total score | 13.8±6.6 | 1.02 (0.98, 1.06) | 0.30 |
| Percent drinking days | 62.2±24.3 | 1.00 (0.99, 1.01) | 0.48 |
| Percent heavy drinking days | 60.6±24.6 | 1.00 (0.99, 1.01) | 0.53 |
| Days since last drink | 22.0±4.2 | 1.03 (0.96, 1.09) | 0.43 |
Abbreviations: BDI, Beck Depression Inventory; CI, confidence interval; HR, hazard ratio; OCDS, Obsessive Compulsive Drinking Scale.