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. 2015 Mar 4;92(3):486–491. doi: 10.4269/ajtmh.14-0231

Table 2.

Patterns of neutralization antibody to DENV in 10- to 18-year-olds with IgG anti-DENV at enrollment in Puerto Rico in 2007

Anti-DENV neutralization patterns* at enrollment Age in years, n (%) Total
10–11 12–13 14–15 16–18
Negative for anti-DENV IgG 8 (15.4) 8 (16.5) 7 (32.7) 3 (15.4) 26 (19.6)
Past DENV infection, single serotype 15 (28.5) 14 (25.7) 9 (26.1) 8 (30.6) 46 (27.5)§
 DENV-1 0 1 (12.2) 0 2 (19.5) 3 (7.4)
 DENV-2 1 (4.9) 6 (42.2) 2 (18.1) 1 (9.8) 10 (19.9)**
 DENV-3 11 (75.3) 5 (37.3) 5 (47.5) 3 (51.1) 24 (53.8)††
 DENV-4 3 (19.7) 2 (8.3) 2 (34.3) 2 (19.6) 9 (18.9)‡‡
Past DENV infection, serotype undetermined 29 (56.1) 33 (57.8) 17 (41.3) 19 (53.9) 98 (52.9)§§
Total 52 55 33 30 170

Calibration weighting was applied to the calculation of all proportions.

*

MNT was used to detect anti-DENV neutralization antibodies in enrollment specimens with a positive IgG anti-DENV ELISA result.

Enrollment specimens with a negative single-dilution (1:100) IgG anti-DENV ELISA result did not receive additional testing.

95% CI = 13.6–27.4%.

§

95% CI = 13.6–27.4%.

Predominant serotype; numbers in parentheses represent the percentages of the total for that past single-serotype DENV infection pattern by age group.

95% CI = 3.2–16.3%.

**

95% CI = 10.5–34.3%.

††

95% CI = 40.4–66.6%.

‡‡

95% CI = 10.2–32.4%.

§§

95% CI = 46.5–59.3%.