Table 3. Comparison of WHODAS scores between control group and each of the gene expanded groups for the best fitting models from Table 2.

	Difference with control
Measure (best model)	Effect	Groups	Estimate	SE	t-value	P-value
Participant	Baseline	Low	0.32	1.12	0.28	0.78
(baseline group effect model)		Med	1.89	0.98	1.94	0.054	+
		High	3.99	0.93	4.28	<0.001	***
Companion	Baseline	Low	1.54	1.13	1.37	0.17
(baseline+longitudinal		Med	1.58	0.99	1.59	0.11
group effect model)		High	3.71	0.98	3.80	<0.001	***
	Longitudinal	Low	−0.72	0.97	−0.74	0.46
		Med	2.09	0.90	2.33	0.020	*
		High	1.95	0.85	2.30	0.022	*

Abbreviations: Med, medium; WHODAS, World Health Organization Disability Assessment Schedule.

***P<0.001, **P<0.01, *P<0.05, ⁺P<0.1.