Table 1.
Exp. | Genotype | Treatment | Mean life span ± SEM (days) | % change | Maximum life span (days) | % change | N (animal) | Significance |
---|---|---|---|---|---|---|---|---|
1 | N2 | Control | 34.8 ± 0.8 | +11 | 54 | −4 | 34 | P < 0.01 |
N2 | 10-HDA 25 µM | 38.7 ± 1.0 | 52 | 26 | ||||
| ||||||||
2 | N2 | Control | 34.4 ± 0.6 | +10 | 49 | +14 | 45 | P < 0.01 |
N2 | 10-HDA 25 µM | 37.7 ± 0.8 | 56 | 29 | ||||
| ||||||||
3 | N2 | Control | 34.3 ± 0.5 | +6 | 45 | +11 | 56 | P < 0.01 |
N2 | 10-HDA 25 µM | 36.2 ± 0.5 | 50 | 95 | ||||
| ||||||||
1 | daf-2 | Control | 61.3 ± 12.3 | +10 | 82 | +20 | 31 | P < 0.01 |
daf-2 | 10-HDA 25 µM | 67.2 ± 11.7 | 98 | 34 | ||||
| ||||||||
2 | daf-2 | Control | 63.7 ± 10.5 | +24 | 87 | +46 | 49 | P < 0.01 |
daf-2 | 10-HDA 25 µM | 79.2 ± 17.5 | 127 | 41 | ||||
| ||||||||
3 | daf-2 | Control | 63.0 ± 11.9 | +14 | 83 | +18 | 53 | P < 0.01 |
daf-2 | 10-HDA 25 µM | 71.8 ± 13.9 | 98 | 61 | ||||
| ||||||||
1 | eat-2 | Control | 32.5 ± 2.8 | +6 | 39 | +25 | 23 | |
eat-2 | 10-HDA 25 µM | 34.5 ± 4.4 | 49 | 21 | ||||
| ||||||||
2 | eat-2 | Control | 39.8 ± 4.8 | −13 | 56 | −14 | 30 | |
eat-2 | 10-HDA 25 µM | 34.8 ± 5.1 | 48 | 11 | ||||
| ||||||||
3 | eat-2 | Control | 37.0 ± 5.3 | −7 | 54 | −4 | 71 | |
eat-2 | 10-HDA 25 µM | 34.4 ± 4.4 | 52 | 83 | ||||
| ||||||||
1 | unc-24/+ | Control | 37.8 ± 0.8 | +4 | 46 | +9 | 58 | |
unc-24/+ | 10-HDA 25 µM | 40.2 ± 1.1 | 50 | 61 | ||||
unc-24/daf-15 | Control | 39.6 ± 1.3 | −5 | 49 | −14 | 71 | ||
unc-24/daf-15 | 10-HDA 25 µM | 36.4 ± 0.6 | 42 | 65 | ||||
| ||||||||
2 | unc-24/+ | Control | 36.6 ± 0.5 | +4 | 46 | +9 | 58 | P < 0.01 |
unc-24/+ | 10-HDA 25 µM | 38.1 ± 0.6 | 50 | 61 | ||||
unc-24/daf-15 | Control | 37.7 ± 0.5 | −5 | 49 | −14 | 71 | ||
unc-24/daf-15 | 10-HDA 25 µM | 35.8 ± 0.4 | 42 | 65 | ||||
| ||||||||
3 | unc-24/+ | Control | 37.7 ± 0.6 | +6 | 47 | +13 | 43 | P < 0.01 |
unc-24/+ | 10-HDA 25 µM | 39.8 ± 0.7 | 53 | 47 | ||||
unc-24/daf-15 | Control | 39.1 ± 0.6 | −5 | 53 | −11 | 85 | ||
unc-24/daf-15 | 10-HDA 25 µM | 37.2 ± 0.4 | 47 | 83 | ||||
| ||||||||
4 | unc-24/+ | Control | 36.5 ± 4.6 | +7 | 46 | +11 | 38 | P < 0.01 |
unc-24/+ | 10-HDA 25 µM | 39.0 ± 5.8 | 51 | 41 | ||||
unc-24/daf-15 | Control | 37.8 ± 5.3 | −3 | 50 | −10 | 37 | ||
unc-24/daf-15 | 10-HDA 25 µM | 36.5 ± 4.1 | 45 | 39 |