Table 1.
Characteristics of pediatric patients with celiac disease.
| CD patients | Thyroid antibodies (+) (n = 11) |
Thyroid antibodies (−) (n = 56) |
P |
|---|---|---|---|
| Age at diagnosis (year) | 3.22 ± 2.21 | 7.47 ± 4.69 | 0.004 |
| Gender (male/female) | 0.57 : 1 (4/7) | 0.6 : 1 (21/35) | 1.00 |
| Weight | |||
| <3rd percentile | 6 (54.5%) | 29 (51.7%) | 1.00 |
| >3rd percentile | 5 (45.4%) | 27 (48.2%) | 0.82 |
| Height | |||
| <3rd percentile | 6 (54.5%) | 27 (48.2%) | 0.75 |
| >3rd percentile | 5 (45.4%) | 29 (51.7%) | 0.70 |
| Clinical presentation | |||
| Typical | 9 (81.8%) | 32 (57.1%) | 0.18 |
| Atypical | 2 (18.1%) | 24 (42.8%) | 0.12 |
| Compliance to GFD | |||
| Compliant | 7 (63.6%) | 30 (53.5%) | 0.74 |
| Noncompliant | 4 (36.3%) | 26 (46.4%) | 0.54 |
| Duration of follow-up | 8.05 ± 3.6 | 6.7 ± 4.1 | 0.31 |
| Laboratory findings | |||
| TSH (mU/L) | 2.92 ± 1.56 | 2.99 ± 1.73 | 0.95 |
| FT4 (ng/dL) | 1.10 ± 0.31 | 1.37 ± 1.39 | 0.58 |
| FT3 (pmol/L) | 3.28 ± 0.98 | 3.25 ± 0.45 | 0.61 |
GFD: gluten-free diet; TSH: thyrotropin (thyroid-stimulating hormone); FT4: free thyroxine; FT3: free triiodothyronine.
P < 0.05 is statistically significant.