Table 3.
Results of SNP association analyses in our sample and in the PGC database
| SNP ID | MAF (cases) | MAF (controls) | SNP association analysis in our sample | SNP association analysis in the PGC database | ||||
|---|---|---|---|---|---|---|---|---|
| OR | X 2 | P value | OR | SE | P value | |||
| rs3848173 | 0.2288 | 0.1667 | 1.484 | 4.768 | 0.029 | |||
| rs17225178 | 0.1966 | 0.1173 | 1.842 | 9.773 | 0.001771 | 1.115 | 0.0433 | 0.0121 |
Nominally significant P values after genetic association analysis between 34 SNPs in ARNT2 and AS in our sample are reported (α = 0.05). Significant P value after Bonferroni correction for total number of SNPs is written in bold and italicized (α = 0.0024). Major allele is the reference allele for the estimated OR. Results of genetic association analysis between rs17225178 and ASC in the PGC database are also reported. AS, Asperger Syndrome; ASC, Autism Spectrum Conditions; MAF, minor allele frequency; OR, odds ratio; PGC, Psychiatric Genomics Consortium; SE, standard error for the odds ratio; SNP, single nucleotide polymorphism.