Fig 3. MAb7F9 attenuates the ability of acute METH to reduce baseline ICSS thresholds, ICSS thresholds (A) and response latencies (B) (expressed as percent of baseline, mean ± SEM) following i.v. infusion of vehicle (PBS) or mAb (30, 100, or 200 mg/kg) followed by repeated daily injections of s.c. SAL or 0.3 mg/kg METH in Experiment 2.

** Significantly different from PBS + SAL at that session, p < 0.01. ^{#, ##} 200 mAb + METH significantly different from PBS + METH at that session, p < 0.05 or 0.01. For clarity, significant differences in marginal means between groups are not shown in Fig. 3A or 3B.