Table 3.

Probability of target attainment (PTA) and breakpoints of cefquinome against H. parasuis with recommended regimens (2 mg/kg/24 h and 4 mg/kg/12 h)

Drug regimens	PTA for T% > MIC = 61	PTA for T% > MIC = 71	Susceptibility breakpoint (mg/L)
1 mg/kg/12 h	76.87	72.52	0.3
2 mg/kg/12 h	82.19	80.63	0.6
4 mg/kg/12 h	85.79	84.37	1.3
6 mg/kg/12 h	86.46	85.88	1.9
8 mg/kg/12 h	87.64	86.76	2.6
16 mg/kg/12 h	90.03	88.55	5.2
2 mg/kg/24 h	44.79	28.18	0.06
4 mg/kg/24 h	61.77	43.52	0.15
8 mg/kg/24 h	76.91	61.6	0.3
16 mg/kg/24 h	81.25	77.21	0.6
32 mg/kg/24 h	86.06	82.21	1.2
60 mg/kg/24 h	86.64	84.74	2.2