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. 2015 Mar 5;10(3):e0119152. doi: 10.1371/journal.pone.0119152

Table 1. Firing rates of GP, STN and SNr neurons before and after dopamine or quinpirole injection into the GP.

FR increase cells FR decrease cells Non responsive cells
Before After Before After Before After
GP neurons
Dopamine 18.64±1.62 27.03±2.44*** 21.15±8.95 15.20±9.43* 22.63±2.07 22.63±2.12ns
Quinpirole 14.31±2.14 19.44±2.72** 20.22±3.31 10.87±1.56** 24.68±3.96 25.61±3.99ns
STN neurons
Dopamine 4.72±0.60 6.66±0.96* 5.12±0.79 3.43±0.56* 6.39±0.72 6.22±0.60ns
Quinpirole 11.92±6.69 18.86±4.10* 11.36±2.51 7.23±1.43* 12.91±2.48 13.33±2.67ns
SNr neurons
Dopamine 9.03±2.90 13.10±3.78* 9.41±1.24 5.73±1.03* 12.30±4.16 12.54±4.64ns
Quinpirole 21.82±6.00 32.12±7.40* 16.10±2.11 8.99±1.60* 12.91±2.48 13.33±2.67ns

FR: firing rate in spikes/sec; values are presented as the mean ± SEM. Statistical analysis using paired t-test was performed;

*: p<0.05,

**: p<0.01,

***: p<0.001 in comparison with before drug injection.