Table 1.
The univariate analysis on the hematoma enlargement (%).
| Factor | Hematoma enlargement (%) (n = 43) | Nonhematoma enlargement (%) (n = 213) | Value | P |
|---|---|---|---|---|
| Age (yrs) | 66.00 ± 24.00 | 65.00 ± 22.00 | −0.578△ | 0.563 |
| Male | 35 (81.4) | 138 (64.8) | 4.503⋄ | 0.034* |
| Hypertension history | 27 (62.80) | 139 (65.30) | 0.096⋄ | 0.757 |
| DM history | 4 (9.30) | 25 (11.70) | 0.038● | 0.845 |
| ICH history | 4 (9.30) | 13 (6.10) | 0.591⋄ | 0.442 |
| Alcohol intake | ||||
| Yes | 11 (25.6) | 44 (20.7) | ||
| Stopped | 1 (2.3) | 10 (4.7) | 0.903⋄ | 0.637 |
| No | 31 (72.1) | 159 (74.6) | ||
| Smoking | ||||
| Yes | 14 (32.60) | 47 (22.10) | ||
| Stopped | 3 (7.00) | 35 (16.40) | 3.814⋄ | 0.149 |
| No | 26 (60.50) | 131 (61.50) | ||
| Duration from onset to the first CT scan (hrs) | ||||
| 0~1 | 6 (14.0) | 10 (4.7) | ||
| >1~2 | 9 (20.90) | 20 (9.40) | ||
| >2~4 | 13 (30.20) | 59 (27.70) | 9.952# | 0.002* |
| >4~6 | 3 (7.00) | 26 (12.20) | ||
| >6~24 | 12 (27.90) | 98 (46.00) | ||
| Baseline systolic blood pressure (mmHg) | 176.42 ± 31.09 | 167.82 ± 25.84 | −1.920▲ | 0.056 |
| Baseline GCS | ||||
| 3~7 | 4 (9.30) | 4 (1.90) | ||
| 8~13 | 17 (39.5) | 45 (21.1) | 12.995# | 0.000* |
| 14~15 | 22 (51.2) | 164 (77.0) | ||
| Baseline NIHSS | 10 ± 6 | 5 ± 7 | 3.791△ | 0.000* |
| Hematoma location | ||||
| Basal ganglion | 19 (44.2) | 116 (54.4) | ||
| Thalamus | 4 (9.3) | 37 (17.4) | ||
| Lobar | 16 (37.2) | 46 (21.6) | 6.667⋄ | 0.155 |
| Cerebellar | 1 (2.3) | 6 (2.8) | ||
| Brain stem | 3 (7.0) | 8 (3.8) | ||
| Intraventricular hemorrhage | 5 (11.6) | 28 (13.1) | 0.073⋄ | 0.786 |
| Hematoma volume (mL) | ||||
| ≤15 | 28 (65.1) | 166 (77.9) | ||
| >15~30 | 9 (20.9) | 33 (15.5) | 3.290# | 0.070 |
| >30 | 6 (14.0) | 14 (6.5) | ||
| Irregular hematoma | 34 (79.1) | 139 (65.3) | 3.115⋄ | 0.078 |
| PLT (109/L) | 203.00 ± 82.00 | 209.00 ± 63.50 | −0.768△ | 0.443 |
| PT (s) | 11.50 ± 1.80 | 12.00 ± 1.80 | −0.270△ | 0.787 |
| APTT (s) | 30.00 ± 11.20 | 30.00 ± 9.25 | −0.026△ | 0.979 |
| FIB (g/L) | 3.07 ± 0.63 | 3.09 ± 0.71 | −0.466△ | 0.641 |
| ALT (IU/L) | 28.00 ± 17.00 | 21.00 ± 17.00 | 1.525△ | 0.127 |
| AST (IU/L) | 29.00 ± 11.00 | 24.00 ± 14.00 | 1.969△ | 0.049* |
| Urea (mmol/L) | 5.00 ± 1.44 | 5.00 ± 1.72 | −0.285△ | 0.775 |
| Crea (mmol/L) | 80.00 ± 28.00 | 80.00 ± 23.50 | 0.388△ | 0.698 |
| PBC and RBS herbal | ||||
| Not used | 19 (44.2) | 78 (36.6) | ||
| PBC | 2 (4.7) | 26 (12.2) | 0.181# | 0.149 |
| RBS | 22 (51.2) | 109 (51.2) | ||
| PBC and RBS | 24 (55.8) | 135 (63.4) | 0.870 | 0.390 |
| Leech | 22 (51.2) | 109 (51.2) | 0.00 | 1.00 |
| Leonurus | 24 (58.1) | 124 (58.2) | 0.085 | 0.866 |
| Rhizoma | 22 (51.2) | 109 (51.2) | 0.00 | 1.00 |
Note: * P < 0.05, ▲ t-test, △Mann-Whitney U test, ●continuous correction chi-square test, ⋄Pearson chi-square test, and #Kruskal-Wallis test.