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. 2014 Jun 18;9(2):188–196. doi: 10.5009/gnl13371

Fig. 1.

Fig. 1

Unsupervised hierarchical clustering analysis of gastric cancer formalin-fixed paraffin-embedded tissues. (A) A total of 1,781 microRNA (miRNA) probes were identified as differentially expressed between the cancerous and noncancerous regions of patients with gastric cancer. The higher normalized ratio value denotes higher expression levels of the miRNAs. (B) Two subclasses, Helicobacter pylori (Hp)-positive (n=7) and H. pylori-negative (n=6), showed clustering results of 219 miRNAs that exhibited 2-fold changes in gastric cancer samples. (C) A fold-change graph of 18 miRNAs upregulated in H. pylori-positive cancer. (D) A fold-change graph of 19 miRNAs upregulated in H. pylori-negative cancer.

*p<0.05; p<0.01.