Table 3. Incidence rate changes in prostate cancer treatment modality for non-metastatic disease stratified by age and NICE risk group between 2000–2005 and 2006–2010.
| Age | Risk | Treatment | Percentage 2000–2005 | Percentage 2006–2010 | SE | Z | p-value | Trend |
|---|---|---|---|---|---|---|---|---|
| < 60 years | Low risk | Conservative management | 22.5% | 53.4% | 0.056 | -5.717 | 0.000 | Increase |
| Radical prostatectomy | 46.5% | 26.1% | 0.055 | 3.719 | 0.000 | Decrease | ||
| Radical radiotherapy | 26.4% | 16.1% | 0.047 | 2.192 | 0.028 | Decrease | ||
| PADT | 5.6% | 4.3% | 0.025 | 0.487 | 0.626 | No change | ||
| Intermediate risk | Conservative management | 5.8% | 13.3% | 0.034 | -2.194 | 0.028 | Increase | |
| Radical prostatectomy | 52.1% | 55.1% | 0.055 | -0.560 | 0.575 | No change | ||
| Radical radiotherapy | 33.9% | 27.4% | 0.050 | 1.300 | 0.194 | No change | ||
| PADT | 8.3% | 4.2% | 0.025 | 1.634 | 0.102 | No change | ||
| High risk | Conservative management | 1.3% | 5.2% | 0.020 | -1.990 | 0.047 | Increase | |
| Radical prostatectomy | 31.4% | 38.1% | 0.050 | -1.349 | 0.177 | No change | ||
| Radical radiotherapy | 49.7% | 37.2% | 0.051 | 2.417 | 0.016 | Decrease | ||
| PADT | 17.6% | 19.5% | 0.041 | -0.451 | 0.652 | No change | ||
| 60–69 | Low risk | Conservative management | 28.2% | 61.0% | 0.037 | -8.877 | 0.000 | Increase |
| Radical prostatectomy | 25.5% | 15.9% | 0.030 | 3.212 | 0.001 | Decrease | ||
| Radical radiotherapy | 37.3% | 18.9% | 0.033 | 5.577 | 0.000 | Decrease | ||
| PADT | 9.1% | 4.2% | 0.018 | 2.679 | 0.007 | Decrease | ||
| Intermediate risk | Conservative management | 13.8% | 21.4% | 0.022 | -3.421 | 0.001 | Increase | |
| Radical prostatectomy | 23.8% | 27.2% | 0.025 | -1.345 | 0.179 | No change | ||
| Radical radiotherapy | 49.6% | 42.7% | 0.028 | 2.428 | 0.015 | Decrease | ||
| PADT | 12.9% | 8.8% | 0.017 | 2.390 | 0.017 | Decrease | ||
| High risk | Conservative management | 2.0% | 4.4% | 0.009 | -2.567 | 0.010 | Increase | |
| Radical prostatectomy | 16.2% | 25.9% | 0.021 | -4.630 | 0.000 | Increase | ||
| Radical radiotherapy | 46.9% | 47.7% | 0.025 | -0.307 | 0.759 | No change | ||
| PADT | 34.9% | 22.0% | 0.023 | 5.690 | 0.000 | Decrease | ||
| 70–79 | low risk | Conservative management | 48.9% | 79.0% | 0.045 | -6.692 | 0.000 | Increase |
| Radical prostatectomy | 2.7% | 0.0% | 0.011 | 2.532 | 0.011 | Decrease | ||
| Radical radiotherapy | 24.9% | 11.6% | 0.036 | 3.682 | 0.000 | Decrease | ||
| PADT | 23.5% | 9.4% | 0.035 | 4.062 | 0.000 | Decrease | ||
| Intermediate risk | Conservative management | 26.1% | 33.9% | 0.024 | -3.294 | 0.001 | Increase | |
| Radical prostatectomy | 1.5% | 4.5% | 0.009 | -3.252 | 0.001 | Increase | ||
| Radical radiotherapy | 33.5% | 35.5% | 0.025 | -0.808 | 0.419 | No change | ||
| PADT | 38.9% | 26.1% | 0.024 | 5.389 | 0.000 | Decrease | ||
| High risk | Conservative management | 2.0% | 5.4% | 0.008 | -4.077 | 0.000 | Increase | |
| Radical prostatectomy | 1.6% | 4.0% | 0.007 | -3.278 | 0.001 | Increase | ||
| Radical radiotherapy | 26.9% | 36.3% | 0.020 | -4.642 | 0.000 | Increase | ||
| PADT | 69.5% | 54.3% | 0.021 | 7.209 | 0.000 | Decrease | ||
| >80+ | low risk | Conservative management | 78.3% | 86.7% | 0.104 | -0.808 | 0.419 | NA |
| Radical prostatectomy | 0.0% | 0.0% | 0.000 | N/A | NA | |||
| Radical radiotherapy | 0.0% | 0.0% | 0.000 | N/A | NA | |||
| PADT | 21.7% | 4.7% | 0.065 | 2.622 | 0.009 | NA | ||
| Intermediate risk | Conservative management | 36.2% | 58.3% | 0.053 | -4.129 | 0.000 | NA | |
| Radical prostatectomy | 0.0% | 0.0% | 0.000 | N/A | NA | |||
| Radical radiotherapy | 6.6% | 5.3% | 0.025 | 0.493 | 0.622 | NA | ||
| PADT | 57.2% | 36.4% | 0.053 | 3.914 | 0.000 | NA | ||
| High risk | Conservative management | 6.3% | 14.8% | 0.020 | -4.186 | 0.000 | NA | |
| Radical prostatectomy | 0.0% | 0.0% | 0.000 | N/A | NA | |||
| Radical radiotherapy | 5.3% | 5.5% | 0.015 | -0.098 | 0.922 | NA | ||
| PADT | 88.4% | 79.7% | 0.024 | 3.592 | 0.000 | NA |