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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: FEBS J. 2015 Jan 27;282(5):864–873. doi: 10.1111/febs.13185

Figure 6.

Figure 6

Inhibition of clotting time. A) mA1-A1ND inhibits the clotting time in plasma samples of APS patients positive for anti-β2GPI antibodies. Normal plasma (gray bars); normal plasma supplemented with anti-β2GPI antibodies and anti-β2GPI positive patients’ plasma (blue bars); normal plasma with anti-β2GPI antibodies and patients’ plasma in the presence of either 4 μM or 17 μM of mA1-A1ND (red bars) and normal plasma containing either 4 μM or 17 μM of mA1-A1ND (hatched bars). (B) mA1-A1 and mA1-A1ND inhibit equally well the prolongation of clotting time in plasma samples of APS patients positive for anti-β2GPI antibodies. APS plasma (blue bars), APS plasma in the presence of either 4 μM or 17 μM of mA1-A1ND (red bars) and mA1-A1 (orange bars). Results are expressed as mean and deviation from the mean calculated from 2 to 3 independent experiments.