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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Apoptosis. 2015 Apr;20(4):551–561. doi: 10.1007/s10495-015-1105-5

FIG. 1. Effect of HN on Doxorubicin-induced male germ cell apoptosis in seminiferous tubule culture.

FIG. 1

Quantification of apoptotic cells in squashed seminiferous tubules after treatment ex vivo. The rate of germ cell apoptosis is similar between control and HN groups (p<0.05). High dose, but not low dose, of doxorubicin (DOX) significantly increased the number of apoptotic cells compared with control (p<0.05). Humanin treatment significantly attenuated germ cell apoptosis induced by high dose of DOX treatment (p<0.05). Values are the mean ± SEM. Means with unlike superscripts are significantly different (P<0.05).