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. 2015 Mar 7;21(9):2700–2710. doi: 10.3748/wjg.v21.i9.2700

Table 4.

Summarized data of microsatellite instability status, expression of mismatch repair proteins and KRAS mutations

MSI Expression of MMR protein
KRAS mutation base exchange (codon) Age Gender
MLH1 MSH2
Case 6 MSI-H + + - 55 M
Case 36 MSI-H + - - 85 M
Case 31 MSI-H - + - 67 M
Case 34 MSI-H + + - 71 M
Case 12 MSI-L + + GGT>GAT(12) 69 M
Case 28 MSI-L + - - 41 M
Case 24 MSI-L + + - 60 M
Case 40 MSI-L + + - 35 M
Case 25 MSI-L + + - 53 F
Case 5 MSI-L + + - 23 F
Case 44 MSI-L + + - 87 F
Case 38 MSI-L + + - 67 F
Case 41 MSS + + GGC>GAC(13) 45 F
Case 20 MSS + + GGT>GAT(12) 59 F
Case 46 MSS + + GGT>GTT(12) 40 F

MSI: Microsatellite instability; MSI-H: MSI-high; MSI-L: MSI-low; MMR: Mismatch repair; M: Male; F: Female.