Table 3.

Mutations in KIT Identified from the Extended TGCT Series Analyzed by Direct Sanger Sequencing

Sample ID	Exon	Position	Amino Acid Change
21 TC2⁎	11	1727 T>C	L576P
38 TC1⁎	11	1727 T>C	L576P
14 TC2⁎	17	2446 G>C	D816H
57 TC1†	17	2447 A>C	D816A
13 TC2⁎	17	2447 A>T	D816V
15 TC2⁎	17	2447 A>T	D816V
28 TC1⁎	17	2447 A>T	D816V
39 EGCT‡	17	2447 A>T	D816V
66 TC2⁎	17	2447 A>T	D816V
25 TC1†	17	2466 T>G	N822K
87 TC1†	17	2466 T>G	N822K

Abbreviation: TC1/TC2, first/second tumor of a bilateral TGCT pair.

^⁎Patient with bilateral metachronous TGCT (> 2 months before subsequent TGCT).

^†Patient with bilateral synchronous TGCT (≤ 2 months before subsequent TGCT).

^‡Patient with EGCT and unilateral TGCT.