Phenotypic analysis of NU12 tumors.
Phenotypic analysis of NU12 tumors of mice treated with sunitinib. Mice were injected intravenously with 111In-Girentuximab (0.4 MBq, 5 μg) 3 days pre-sunitinib treatment. Accumulation of Girentuximab remained unchanged when sunitinib followed Girentuximab injection. Tumors shown were harvested at Day 7 (4 days after start of sunitinib treatment). A, C: HE staining of untreated and sunitinib treated tumor respectively; B, D: Girentuximab accumulation. Original magnification X25 and X200.