Table 1. SNPs in the OAS family.
| Gene | SNP | Associated clinical phenotype | Location | Nucleotide change | SNP effect |
|---|---|---|---|---|---|
| Oas1 | rs10774671 | WNV | Intron | G/A | Different splicing |
| T1D | |||||
| rs12307655 | HPV | Intron | C/T | ||
| rs2660 | SARS | Exon6 | A/G | Arg/Gly substitution | |
| HCV | |||||
| Oas2 | rs2010604 | SVR | 3′ UTR | G/C | |
| rs1293762 | SVR | Intron | T/G | ||
| TBEV | |||||
| rs15895 | TBEV | 3′ UTR/exon11 | A/G | Early stop codon | |
| rs1732778 | TBEV | 3′ UTR | G/A | ||
| rs718802 | HPV | 3′ UTR | C/A | ||
| Oas3 | rs2285932 | TBEV | Exon6 | T/C | Synonymous |
| rs2072136 | HBV | Exon2 | C/G | Synonymous | |
| TBEV | |||||
| rs12302655 | HPV | 5′ UTR | G/A | ||
| Oasl | rs1169279 | SVR | 3′ UTR | A/G | |
| rs3213545 | SVR | Exon2 | C/T | Synonymous | |
| WNV | |||||
| MCRT | |||||
| rs2859398 | SVR | Promoter | C/T |
Abbreviations: HCV, hepatitis C virus;54 HPV, human papillomavirus;55 MCRT, multiple cardiovascular-related traits; OAS, oligoadenylate synthase; SARS, severe acute respiratory syndrome;56 SNP, single-nucleotide polymorphism; SVR, sustained virologic response; TBEV, tick-borne encephalitis virus;58 T1D, type I diabetes;57 UTR, untranslated region; WNV, West Nile Virus.