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. 2015 Mar 6;5:8824. doi: 10.1038/srep08824

Figure 3. Activity of Ga-NP against co-infections.

Figure 3

(A). Prolonged activity of Ga-NP against HIV-mycobacterium co-infection; intensity of HIV infection was tested by p24 staining. Ga-NP was able to reduce the HIV growth similar to the individual HIV infection up to 15 days. (B). Prolonged activity of Ga-NP against HIV-mycobacterium co-infection; intensity of HIV growth was tested by reverse transcriptase activity assay. There was less than 1% growth on days 1 and 5 for Ga-NP loaded macrophages. On day 15 around 25% growth of HIV was seen, better than free Ga particles. Data are analysed using the t-test. Data are shown as mean +/− s.e.m. for n = 9, P < 0.05. (C). Prolonged-acting property of Ga-NP against HIV-mycobacterium co-infection; mycobacterium growth was measured by CFU counting. Ga nanoparticle showed 7-fold less growth even after 15 days of single drug loading. Data are analysed using the t-test. Data are shown as mean +/− s.e.m. for n = 3, P < 0.05.