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. Author manuscript; available in PMC: 2015 Mar 6.
Published in final edited form as: FEBS Lett. 1986 Apr 21;199(2):269–274. doi: 10.1016/0014-5793(86)80493-8

Fig. 1.

Fig. 1

Stimulation of adenylate cyclase activity of human platelet membranes by NECA in the absence ( Inline graphic) and presence of XAC (2 nM, Inline graphic; 20 nM, Inline graphic; 200 nM, Inline graphic). Adenylate cyclase activity was determined at 37°C for 90 min. Right: Schild plot of the same data with the concentration ratio (CR) of the EC50 values for NECA in the presence and absence of XAC vs the XAC concentration (slope, 1.05; r = 0.9993). EC50 values for NECA: 0.255 μM in the absence and 0.27, 0.46 and 2.29 μM in the presence of 2, 20 and 200 nM XAC, respectively. Values are means of a typical experiment done in triplicate.