Figure 4. The RRN3P2 locus and its distally associated CpG sites.
(a) UCSC browser illustration of the gene structure and location of SNPs associated with distal CpG sites. (b) Association in cis between expression of RRN3P2 in CD4 cells and rs12933229. (c) UCSC browser illustrations of selected associated distal CpG sites and their annotated genes (from top to bottom: BRF1, ELMOD2, MICALL2 and UNKL). (d) Corresponding boxplot representations of the SNP/CpG associations. (e) Corresponding boxplot representations of the association in trans between expression of the genes in CD4 cells with rs12933229.