Table 5.
Univariate Predictors of HRCT Abnormalities
| Estimate | Log Odds Ratio | 95% CI | P Value | |
|---|---|---|---|---|
| PBMC telomere percent | 0.42 | −0.53 to 1.38 | 0.375 | |
| AEC telomere | −0.68 | −1.13 to −0.23 | 0.005 | |
| EBV | 0.33 | −0.81 to 1.47 | 0.56 | |
| CMV | −0.13 | −1.56 to 1.29 | 0.853 | |
| Muc5B quant | 0.07 | −0.48 to 0.62 | 0.804 | |
| BAL cells | 0.32 | −0.08 to 0.72 | 0.11 | |
| Macrophages | −0.05 | −0.27 to 0.16 | 0.623 | |
| Neutrophils | 0.01 | −0.6 to 1.11 | 0.986 | |
| Lymphocytes | 0.13 | −0.76 to 1.01 | 0.767 | |
| SP-D | 0.61 | 0.07 to 1.15 | 0.029 | |
| MMP7 | 0.65 | 0.14 to 1.16 | 0.015 | |
| ET1 | 0.27 | −0.17 to 0.71 | 0.218 | |
| TIMP2 | −0.22 | −0.51 to 0.08 | 0.141 | |
| Age | 0.186 | 0.06 to 0.32 | 0.005 | |
| Sex | 0.631 | −0.98 to 2.24 | 0.444 | |
| Ever smoker | 1.94 | 0.15 to 3.74 | 0.034 |
Definition of abbreviations: AEC = alveolar epithelial cells; BAL = bronchoalveolar lavage; CI = confidence interval; CMV = cytomegalovirus; EBV = Epstein-Barr virus; HRCT = high-resolution computed tomography; MMP = matrix metalloproteinase; PBMC = peripheral blood mononuclear cell; SP-D = surfactant protein-D.