Table I.
Patient characteristics
| Variable | TIF-1γ* 46 (34.3%) |
Mi-2* 8 (6.0%) |
NXP2* 13 (9.7%) |
SAE1 9 (6.7%) |
Jo-1* 6 (4.5%) |
MDA5 17 (12.7%) |
None 23 (17.2%) |
All n = 134 |
P value† |
|---|---|---|---|---|---|---|---|---|---|
| Sex, n (%) | .055 | ||||||||
| Male | 7 (15) | 3 (38) | 8 (62) | 2 (22) | 1 (17) | 4 (24) | 8 (35) | 37 (28) | |
| Female | 39 (85) | 5 (63) | 5 (38) | 7 (78) | 5 (83) | 13 (76) | 15 (65) | 97 (72) | |
| Age at diagnosis, y, mean (SD) | 49.5 (15.9) | 55.2 (11.0) | 51.8 (18.4) | 48.0 (15.9) | 45.7 (12.8) | 46.4 (15.4) | 43.1 (19.0) | 48.4 (16.4) | .67 |
| Race, n (%) | .0081 | ||||||||
| African American | 1 (2) | 1 (12.5) | 0 (0) | 0 (0) | 1 (16.7) | 1 (5.9) | 2 (8.7) | 6 (5) | |
| Asian | 3 (7) | 1 (12.5) | 2 (15.4) | 0 (0) | 1 (16.7) | 6 (35.3) | 2 (8.7) | 15 (11) | |
| Caucasian | 33 (72) | 3 (37.5) | 9 (69.2) | 6 (66.7) | 4 (66.7) | 6 (35.3) | 18 (78.3) | 88 (66) | |
| Latino | 6 (13) | 3 (37.5) | 1 (7.7) | 3 (33.3) | 0 (0) | 0 (0) | 1 (4.4) | 16 (12) | |
| Pacific Islander | 2 (4) | 0 (0) | 1 (7.7) | 0 (0) | 0 (0) | 4 (23.5) | 0 (0) | 8 (6) | |
| Follow-up, y, mean (SD) | 5.0 (3.9) | 5.6 (11.0) | 8.2 (10.2) | 6.4 (4.9) | 3.5 (2.5) | 4.3 (3.9) | 7.9 (4.7) | 5.3 (5.1) | .068 |
| Tobacco [yes or past], n (%) | 6 (14) | 3 (37.5) | 4 (28.6) | 4 (44.4) | 1 (16.7) | 2 (11.8) | 4 (17.4) | 28 (20.9) | .58 |
MDA5, Melanoma differentiation-associated gene 5; NXP2, nuclear matrix protein 2; SAE1, SUMO1 activating enzyme subunit 1; TIF, transcriptional intermediary factor.
*
Does not include patients with >1 antibody.
†
Fisher exact test was used to compare categorical variables and Student t test was used to compare continuous variables.