Table 4.

Between-Groups Activation Differences, by Task Condition.

	Primary Regions	Size (Voxels)	Max T-Statistic	MNI-Coordinates of Peak (x, y, z)
0-Back
HIV/HCV Coinfected > HIV Seronegative a
	Left occipital	7	3.92	−32, −86, −4
	Left occipital	8	3.94	−26, −82, 0
	Right cerebellum	88	4.19	10, −58, −50
	Bilateral cerebellum	1315	5.53	−34, −70, −30
2-Back
HIV/HCV Coinfected > HIV Seronegative a
	Right postcentral	20	3.32	6, −40, 64
	Right angular gyrus	65	4.2	40, −52, 26
	Left SMA	99	3.99	−8, −20, 48
	Bilateral cerebellum	345	5.75	−36, −70, −30
	Bilateral precentral	1546	8.35	44, −8, 56
	Bilateral frontal; left insula/BG	6105	4.63	−2, 44, 44
HIV/HCV Coinfected > HIV Seropositive a
	Right frontal	12	5.1	30, 8, 36
	Right cerebellum	20	5.22	18, −84, −28
	Right precentral	42	7.79	42, −8, 54
	Right precuneus/occipital	46	5.64	10, −60, 46
	Left cerebellum	89	5.76	−36, −72, −30
2-Back > 0-Back
HIV Seronegative > HIV Seropositive a
	Left thalamus/BG	14	4.53	−12, 2, −4
	Right inferior temporal	38	3.84	54, −48, −20
	Bilateral parietal; left occipital/cerebellum	10975	5.28	28, −64, 30

^aFamily-wise p = 0.95; Voxel-wise p = 0.001

Note. BG, Basal Ganglia; SMA, Supplementary Motor Area. All regions presented show significant between-group comparisons for clinical groups (i.e., HIV+, HIV-seronegative, and HIV/HCV coinfected), by task condition (i.e., 0-back, 2-back, and 2-back > 0-back). Exact significance levels are presented for each analysis; these are impacted by contrast type and sample size (i.e., group size). Coordinates represent peak activation voxel.