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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Cancer Res. 2015 Jan 14;75(5):858–869. doi: 10.1158/0008-5472.CAN-14-2289

Fig. 1. hSSB1 interaction with DNA.

Fig. 1

(A) Electrophoretic mobility shift analysis showing preferential binding of recombinant SSB1 to single stranded DNA substrates which are either G- or C-rich telomere oligonucleotides. (B) The data is from triplicate gel shift experiments showing binding curves of hSSB1 using G- and C-rich oligonucleotides. hSSB1 preferentially binds G-rich oligonucleotides with minimum binding to C-rich oligonucleotides. The difference in hSSB1 binding with G-rich vs. C-rich oligonucleotides is statistically significantly (*P < 0.05 and **P < 0.01 as determined by the chi-square test).