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. 2015 Mar 1;4:21. doi: 10.1186/s13643-015-0001-y

Table 2.

Meta-regression of study characteristics on log odds ratio for response

Variable Coefficient 95% confidence interval P value Residual I 2
Dosea 0.01 −0.02 to 0.04 0.46 67%
Unpublished −0.44 −1.04 to 0.16 0.13 74%
Poor quality 0.44 −0.57 to 1.45 0.35 77%
Poor quality or unpublished study −0.23 −0.84 to 0.38 0.42 78%
Non-US-based study −0.70 −1.02 to -0.35 0.001 24%
Duration 8 weeks (vs 6 weeks) 0.10 −0.29 to 0.48 0.58 77%
Baseline MADRS score −0.11 −0.33 to 0.11 0.29 75%
Proportion of study participants non-White −0.04 −0.05 to -0.02 <0.001 0%

aPlacebo arm partitioned for multi-arm trial.