Table 2.
Variable | Mean (S.E) | ||||
---|---|---|---|---|---|
Pre | Post | Mean difference (95% CI) | P- Value | Pre-post change (%) | |
Entire group (EDSS range 2–6.5) (n = 312) | |||||
10mWT (s) | 15.4 (0.7) | 13.0 (0.6) | −2.3 (−1.4, −3.3) | <0.001* | −10.1 (1.7) |
20mWT (s) | 33.8 (1.7) | 29.0 (1.6) | −4.8 (−2.7, −6.9) | <0.001* | −10.6 (1.7) |
2mWT (m) | 120.8 (3.1) | 136.1 (3.8) | 15.3 (11.2, 19.5) | <0.001* | 14.9 (1.9) |
TUG (s) | 15.8 (0.8) | 14.2 (0.6) | −1.6 (−0.7, −2.6) | 0.001* | −5.4 (1.6) |
Mild disability (EDSS range <4.5) (n = 87) | |||||
10mWT (s) | 9.5 (0.5) | 8.4 (0.4) | −1.1 (−1.7, −0.6) | <0.001* | −9.2 (2.3) |
20mWT (s) | 20.1 (1.0) | 17.9 (0.8) | −2.1 (−0.9, −3.4) | 0.001* | −7.7 (2.3) |
2mWT (m) | 143.2 (4.3) | 158.1 (5.6) | 14.9 (8.7, 21.1) | 0.001* | 10.9 (2.3) |
TUG (s) | 9.8 (0.5) | 8.9 (0.3) | −0.9 (−1.5, −0.3) | 0.006* | −5.1 (2.4) |
Moderate disability (EDSS = 4.5-5.5) (n = 104) | |||||
10mWT (s) | 11.5 (0.5) | 9.9 (0.4) | −1.6 (−1.0, −2.2) | <0.001* | −10.3 (2.1) |
20mWT (s) | 24.5 (1.0) | 21.2 (1.1) | −3.4 (−2.1, −4.7) | <0.001* | −11.3 (1.9) |
2mWT (m) | 120.3 (4.2) | 140.6 (5.2) | 20.3 (13.1, 27.5) | <0.001* | 19.0 (3.4) |
TUG (s) | 12.3 (1.1) | 10.8 (0.4) | −1.5 (−0.6, 3.5) | 0.156 | −3.9 (2.3) |
Severe disability (EDSS 6.0-6.5) (n = 121) | |||||
10mWT (s) | 23.2 (1.5) | 19.2 (1.4) | −4.0 (−6.4, −1.6) | 0.001* | −10.5 (3.9) |
20mWT (s) | 52.3 (3.6) | 43.1 (3.7) | −9.2 (−14.1, −4.2) | <0.001* | −12.1 (3.7) |
2mWT (m) | 94.5 (7.4) | 113.1 (11.2) | 18.6 (6.7, 30.6) | 0.004* | 16.2 (5.4) |
TUG (s) | 23.8 (1.6) | 21.4 (1.4) | −2.4 (−4.2, −0.6) | 0.011* | −6.8 (3.1) |
EDSS- expanded disability status scale; 10mWT- ten-meter walking test; 20mWT- twenty-meter walking test; 2mWT- two-minute walking test; TUG - timed up and go test. *P<0.05.