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. 2015 Mar 6;10(3):e0119792. doi: 10.1371/journal.pone.0119792

Table 4. Amino acid substitutions, associated with mammalian host adaptation, receptor binding and antiviral resistance, in the proteins of the four imported H7N9 viruses.

Virus Collection date PB2 PB1-F2 HA NA* M2 NS1
(mm/dd/yy) 627 701 66 226 228 119 292 31 92
A/Anhui/1/2013 03/20/2013 K D N L G E R N D
A/Taiwan/1/2013 04/24/2013 K D N P G E R/K # N D
A/Taiwan/3/2013 12/27/2013 K D N L G E R N D
A/Taiwan/1/2014 04/21/2014 K D N L G E R N D
A/Taiwan/2/2014 04/24/2014 E N N L G E R N D
Substitutions E627K D701N N66S Q226L G228S E119V R292K S31N D92E

#Mixed amino acid residues were detected.