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. 2015 Mar 6;10(3):e0121402. doi: 10.1371/journal.pone.0121402

Fig 5. Zileuton treatment reduces the tumor infiltrating inflammatory cells in polyps.

Fig 5

A) 1, 3, 5, 7: representative APCΔ468/+ polyps; 2, 4, 6, 8: representative Zileuton treated APCΔ468/+ polyps. B) calculation of positive cells as % frequency to the total cells; Black bars APCΔ468/+, and open bars APCΔ468/+ Zileuton treated. C) LTB4 ELISA of B6 (gray bars), APCΔ468/+ (black bars), and APCΔ468/+ Zileuton treated (open bars). D) ELISA human biopsy extracts. C) LTB4 ELISA of B6 (gray bars), APCΔ468/+ (black bars), and APCΔ468/+ Zileuton treated (open bars). D) ELISA human biopsy extracts. Black bars healthy tissue, Open bars tumor extracts. one tailed unpaired t test with Welch’s correction, * P<0.05, **P<0.005, one tail unpaired t test.