Table 4. Age differences in baseline EPA and DHA in plasma fractions, cells and AT.
| Young1 | Middle1 | Old1 | Adjusted mean difference Middle vs. Young2 | Adjusted mean difference Old vs. Young2 | P 3 | |
|---|---|---|---|---|---|---|
| n | 66 | 68 | 69 | |||
| EPA | ||||||
|
| ||||||
| Plasma PC | 1.15 (0.99) | 1.08 (0.37) | 1.22 (0.58) | 0.09 [−0.10, 0.29] | 0.20 [0.00, 0.39] | 0.13 |
| Plasma CE | 0.97 (0.79) | 1.07 (0.68) | 1.20 (0.56) | 0.18 [−0.09, 0.45] | 0.21 [−0.06, 0.48] | 0.27 |
| Plasma NEFA | 0.47 (0.58) | 0.38 (0.26) | 0.42 (0.32) | −0.07 [−0.24, 0.10] | −0.04 [−0.21, 0.13] | 0.73 |
| Plasma TAG | 0.42 (1.01) | 0.19 (0.20) | 0.33 (0.35) | −0.03 [−0.14, 0.08] | 0.09 [−0.02, 0.19] | 0.08 |
| MNC | 0.65 (0.47) | 0.75 (0.55) | 0.85 (0.61) | 0.21 [0.02, 0.43] | 0.26 [0.03, 0.48] | 0.07 |
| RBC | 1.86 (1.35) | 1.89 (1.66) | 2.60 (3.36) | 0.49 [−0.17, 1.14] | 0.56 [−0.09, 1.21] | 0.21 |
| PLAT | 1.11 (0.77) | 1.06 (0.36) | 1.20 (0.75) | −0.03 [−0.28, 0.22] | 0.12 [−0.12, 0.37] | 0.39 |
| BU | 1.96 (4.91) | 1.30 (1.66) | 1.21 (1.49) | −0.92 [−2.20, 0.37] | −0.77 [−2.05, 0.50] | 0.37 |
| AT | 0.14 (0.06) | 0.16 (0.05) | 0.19 (0.06) | 0.01 [−0.02, 0.03] | 0.04 [0.02, 0.06] | 0.003 |
|
| ||||||
| DHA | ||||||
|
| ||||||
| Plasma PC | 3.67 (1.04) | 3.46 (0.99) | 3.70 (1.49) | −0.05 [−0.54, 0.45] | 0.17 [−0.33, 0.66] | 0.64 |
| Plasma CE | 0.63 (0.22) | 0.67 (0.22) | 0.71 (0.22) | 0.04 [−0.05, 0.13] | 0.08 [−0.01, 0.16] | 0.25 |
| Plasma NEFA | 1.67 (1.36) | 1.55 (1.08) | 1.57 (1.01) | 0.05 [−0.38, 0.49] | 0.05 [−0.39, 0.48] | 0.97 |
| Plasma TAG | 1.07 (1.63) | 0.68 (0.32) | 0.93 0.57) | −0.04 [−0.22, 0.14] | 0.20 [0.02, 0.14] | 0.01 |
| MNC | 1.88 (0.61) | 1.81 (0.43) | 1.99 (0.60) | −0.06 [−0.28, 0.16] | 0.09 [−0.13, 0.31] | 0.37 |
| RBC | 5.24 (1.28) | 5.20 (1.39) | 5.43 (1.66) | −0.03 [−0.61, 0.54] | 0.20 [−0.37, 0.77] | 0.65 |
| PLAT | 2.05 (0.58) | 1.92 (0.51) | 2.13 (0.62) | −0.01 [−0.23, 0.21] | 0.15 [−0.07, 0.37] | 0.23 |
| BU | 0.76 (0.33) | 0.80 (0.27) | 0.88 (0.35) | 0.10 [−0.03, 0.22] | 0.15 [0.02, 0.27] | 0.07 |
| AT | 0.15 (0.07) | 0.18 (0.09) | 0.25 (0.12) | 0.06 [0.02, 0.10] | 0.12 [0.08, 0.16] | <0.001 |
1
Data are mean (SD) with EPA or DHA expressed as a percentage of total fatty acids.
2
Data are mean difference [95% CI] in EPA or DHA expressed as percentage of total fatty acids between different age categories adjusted for BMI.
3
Analysis is baseline regressed on Middle vs. Young and Old vs. Young with a global test for age group presented, adjusted for BMI.