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. Author manuscript; available in PMC: 2015 Mar 6.
Published in final edited form as: Br J Nutr. 2013 Sep 24;111(4):679–689. doi: 10.1017/S0007114513002985

Table 6. Age differences in change in EPA and DHA in plasma fractions, cells and AT following 12-months supplementation with EPA + DHA.

EPA DHA
Middle vs. Young1 Old vs. Young1 P 2 Middle vs. Young1 Old vs. Young1 P 2
Plasma PC 0.27 [−0.10, 0.64] 0.14 [−0.23, 0.51] 0.35 0.30 [−0.28, 0.87] 0.22 [−0.35, 0.79] 0.59
Plasma CE 0.14 [−0.20, 0.47] 0.28 [−0.06, 0.61] 0.26 0.05 [−0.07, 0.17] 0.00 [−0.12, 0.12] 0.68
Plasma NEFA 0.25 [0.04, 0.47] 0.19 [−0.02, 0.41] 0.07 0.20 [−0.37, 0.76] 0.09 [−0.47, 0.66] 0.79
Plasma TAG 0.42 [0.05, 0.78] −0.05 [−0.42, 0.32] 0.02 0.15 [−0.28, 0.59] −0.20 [−0.64, 0.23] 0.23
MNC −0.01 [−0.34, 0.32] −0.18 [−0.51, 0.15] 0.46 0.09 [−0.22, 0.41] −0.01 [−0.33, 0.31] 0.76
RBC −0.46 [−1.56, 0.64] −0.96 [−2.06, 0.14] 0.23 0.14 [−0.53, 0.81] −0.06 [−0.74, 0.61] 0.82
PLAT 0.40 [0.05, 0.75] 0.13 [−0.22, 0.47] 0.07 0.13 [−0.12, 0.37] −0.01 [−0.26, 0.24] 0.45
BU 1.89 [−0.49, 4.27] 1.45 [−0.92, 3.82] 0.28 −0.02 [−0.24, 0.21] −0.19 [−0.42, 0.03] 0.16
AT 0.00 [−0.05, 0.05] −0.01 [−0.06, 0.04] 0.91 −0.03 [−0.09, 0.03] −0.08 [−0.14, −0.02] 0.02
1

Data are mean difference [95% CI] in the change in EPA or DHA expressed as percentage of total fatty acids between different age categories, adjusted for treatment group, compliance and BMI.

2

Analysis is change regressed on Middle vs. Young and Old vs. Young with a global test for age group presented, adjusted for treatment group, compliance and BMI.