Table 5.
Correlation between hyposalivation and its causes and consequences in study group (with NF1)
| Variables | Hyposalivation | ||
|---|---|---|---|
| UWSFR | OR (95% IC) | P * | |
| Age | 43 ± 15.6† | – | 0.77 |
| Female/Male | 23/6 (3.8/1) | 2.5 (0.7-9.0) | 0.14 |
| Plexiform neurofibroma close to or involving major salivary glands areas | 1 (3.4%) | 0.2 (0.01-2.1) | 0.29 |
| Smoker | 1 (3.4%) | 0.2 (0.01-2.1) | 0.29 |
| Alcohol user | 5 (17%) | 1.1 (0.2-5.6) | 1.0 |
| Hyposalivation-inducing drugs | 15 (51%) | 1.6 (0.5-5.0) | 0.41 |
| Intake less than 2 liters of liquid daily | 8 (27%) | 1.7 (0.5-5.6) | 0.36 |
| Caffeinated or stimulant drink use | 13 (44%) | 1.2 (0.3-4.1) | 0.68 |
| Mouth breather | 14 (48%) | 1.4 (0.4-4.8) | 0.51 |
| Oral candidiasis | 7 (24%) | 1.2 (0.3-5.0) | 1.0 |
| Tongue coating index | 44.4 ± 27.3† | – | 0.05 |
UWSFR, Unstimulated whole saliva flow rate; OR (95% IC), Odds ratio and 95% of confidence interval.
*P value is from Qui-square analysis and Fisher’s exact tests for categorical variables and Mann–Whitney test for numerical variables; †Results of age and tongue coating index indicate mean ± standard deviation.