Skip to main content
. 2015 Mar 6;10(3):e0119101. doi: 10.1371/journal.pone.0119101

Table 4. Impact of prognostic factors on treatment results by univariate analysis.

Items 5y-LFFS 5y-RFFS 5y-DFFS 5y-OS
% p % p % p % p
Gender
 Male 85.1 .662 93.9 .679 74.6 .433 62.9 .211
 Female 88.4 95.5 80.6 73.4
Age
 ≥50 y 83.4 .599 94.4 .944 78.6 .645 55.2 .011
 <50y 87.9 94.4 74.1 73.9
Involvement of cranial nerves
 NO 89.0 .049 95.8 .176 76.0 .840 71.3 .033
 YES 76.9 90.1 77.3 49.3
N classification
 N0–1 87.5 .922 97.0 .227 82.0 .188 74.4 .347
 N2–3 84.8 92.5 72.3 59.5
Metastasis to (RLN)
 NO 83.4 .307 97.3 .408 74.5 .971 70.7 .585
 YES 86.5 93.5 76.7 63.8
Concurrent chemoradiotherapy
 NO 85.6 .762 90.6 .162 77.4 .788 62.4 .463
 YES 86.0 96.3 75.9 66.8
Boost
 NO 87.9 .368 95.0 .478 76.7 .975 66.7 .422
 YES 80.4 92.6 74.6 60.7
Volume of GTVnx
 >50 ml 75.2 .004 92.8 .453 78.4 .991 52.8 .008
 ≤50ml 94.2 95.5 77.2 78.7

Abbreviations: RLN, retropharyngeal lymph nodes; GTVnx, gross tumor volume of the nasopharynx; LFFS, local failure-free survival; RFFS, regional failure-free survival; DFFS, distant failure-free survival; OS, overall survival.