Table 6. Threshold analysis of post-exposure prophylaxis effectiveness.
PEP effect | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Contact Group | 0 | 0.001 | 0.002 | 0.005 | 0.01 | 0.08 | 0.09 | 0.1 | 0.9 | 1 |
Infant | no | no | A | A | A | A | A | A | A | A |
Child | no | no | no | no | no | no | no | A | A | A |
Adult | no | no | no | no | no | no | A | A | A | A |
“no” indicates no PEP as the preferred option.
“A” indicates azithromycin. When PEP has zero effect, the net benefit of no prophylaxis exceeds that of azithromycin and other macrolides. At or above 10% effectiveness, PEP with azithromycin offers a higher net benefit than no intervention.