Table 4.

Results of genetic association analysis of RSTR phenotype (SNPs with nominal p-values <0.05

SNP	Gene	Location	OR (95% CI)	p	Best Model
rs3024490	IL10	intron	0.59(0.37, 0.96)	0.032	Dom
rs2243115	IL12A	intron	1.72(1.01, 2.92)	0.044	Add
rs17852635	IL12RB1	coding P228P	0.30(0.11, 0.82)	0.019	Dom
rs2066445	IL12RB2	intron	0.62(0.39, 0.99)	0.046	Dom
rs2709800	NOD1	intron	0.53(0.3, 0.96)	0.036	Dom
rs932272	NOD1	intron	0.57(0.34, 0.95)	0.031	Dom
rs6500328	NOD2	intron	2.44(1.01. 5.88)	0.047	Dom
rs2111234	NOD2	intron	1.56(1.07, 2.28)	0.020	Add
rs409588	SLC6A3	intron	0.68(0.5, 0.93)	0.014	Add
rs456082	SLC6A3	intron	0.70(0.51, 0.96)	0.025	Add
rs464061	SLC6A3	intron	0.70(0.51, 0.96)	0.025	Add
rs7575823	STAT1	intron	0.59(0.35, 0.98)	0.043	Dom
rs2052834	TICAM2	flanking 5’ UTR	0.66(0.46, 0.97)	0.032	Add
rs4235232	TLR2	intron	1.83(1.03, 3.24)	0.040	Dom
rs5030710	TLR4	coding S105S	0.46(0.24, 0.88)	0.020	Dom
rs5030729	TLR4	intron	0.48(0.25, 0.91)	0.026	Dom
rs5743942	TOLLIP	intron	2.20(1.19, 4.06)	0.012	Dom