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. Author manuscript; available in PMC: 2016 Feb 4.
Published in final edited form as: Neuron. 2015 Jan 22;85(3):534–548. doi: 10.1016/j.neuron.2014.12.068

Figure 5. Preservation of synaptic integrity in Il10 deficient APP/PS1 mice.

Figure 5

(A, B) Representative microphotographs of synaptophysin labeling in hippocampus (A) or cortex (B) of mice with the indicated genotypes. Lower panels are 3.5x higher magnification of the upper images. Scale bars denote (A) 87 µm or (B), 25 µm.

(C) Quantitation of synaptophysin labeling in hippocampus and cortex is shown as mean ± SEM (n=4 per group); * p< 0.05, ** p<0.01.

(D) Western blot of synaptophysin levels in frontal cortex homogenates of mice with the indicated genotypes. Beta-actin served as a loading control.