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. 2015 Mar;22(3):308–315. doi: 10.1177/1933719114542008

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Figure 3. — Effects of single cell types and coculture on cytokine and growth factor secretion in engineered tissue. Levels of IL-6 (A) and TGF-β1 (B) were measured in the conditioned medium (n = 3). Stromal tissues (S) produce significantly more IL-6 than epithelial tissues, with significantly more IL-6 production with 0 nmol/L estradiol than 10 nmol/L. Coculture (SE) significantly reduced the amount of IL-6 both with 0 and 10 nmol/L estradiol and increased the amount of TGF-β1 secreted in the presence of 10 nmol/L estradiol. # denotes P < .05 compared to all other conditions. IL-6 indicates interleukin 6; TGF-β1, transforming growth factor β1.