TABLE 8.
Outcome differences between lower-protein, lower-energy intervention and control groups1
| ECOT study (33–35) | Timby et al. (36) | Inostroza et al. (37) | Akeson et al. (38) | |
| Age at outcome | 6 y | 12 mo | 24 mo | 12 mo |
| Lower-protein, lower-energy group:standard protein formula:breastfed, n at outcome | 256:256:237 | 73:68:72 | 50:64:56 | 49:22:Not reported |
| Weight difference | 0.67 kg, P = 0.06 | z Score, −0.2 (NS) | 0.86 g/d (P = 0.03) | z Score not provided but reported to be NS |
| Length difference | −0.02 cm, P = 0.65 | z Score, −0.3 (NS) | Not reported | z Score not provided but reported to be NS |
| Obesity risk2 | RR, 2.43; P = 0.02 | Not reported | Not reported | Not reported |
| BMI | 0.51 kg/m2, P = 0.009 | Not reported | Difference, ∼1.0; P = 0.03 | Not reported |
| BMI z score difference | 0.33 | 0.0 | Not reported | Not reported |
1
NS, P > 0.05. Differences shown compare the standard protein, energy group – the lower-protein, lower-energy group (positive values indicate higher values in the standard protein, energy group). ECOT, European Childhood Obesity Trial.
2
Girls and boys were classified (33–35) as obese at 6 y of age if they had a BMI > 19.7 or >19.8 kg/m2, respectively.
3
P value not shown; 95% CI indicates significance.