Table 1.
Laboratory values of patient NBS20LA from 1.5 months to 1 year of age
| Patient Age | 1.5 month | 3 months | 5.5 months | 10 months | Reference Ranges | ||
|---|---|---|---|---|---|---|---|
| Birth to 2 months | 2 months to 4 months | 4 months to 1 year | |||||
| Total WBC cells/uL | 6800 | 5120 | 5500 | 7880 | 5000–17,000 | 5000–17,000 | 5000–17,000 |
| %Neutrophils | 47 | 44 | 58 | 56 | 25–45 | 25–45 | 25–45 |
| %Lymphocytes | 33 | 27 | 23 | 22 | 46–66 | 46–66 | 46–66 |
| %Monocytes | 8 | 19 | 12 | 14 | 2–8 % | 2–8 % | 2–8 % |
| %Eosinophils | 12 | 10 | 7 | 8 | 0–3 | 0–3 | 0–3 |
| CD 3+ T cells/mL (%) | 924 (42) | 259 (24) | 289 (18) | 381 (22) | 1375–7129 (69–93) | 2533–6778 (55–79) | 2889–7995 (59–80) |
| CD 4+ T cells/mL (%) | 660 (30) | 65 (5) | 224 (15.1) | 320 (19) | 1169–5623 (48–75) | 1392–5210 (35–62) | 1786–5141 (38–61) |
| CD 8+ T cells/mL (%) | 242 (11) | 99 (8) | 63 (4) | 72 (4) | 267–1860 (13–33) | 652–2449 (14–30) | 946–2791 (14–34) |
| CD19+ B-cells/mL (%) | 88 (4) | 26 (2) | 72 (5) | 174 (10) | 104–1448 (4–26) | 745–3499 (14–39) | 858–3774 (16–36) |
| CD3-CD16/56+ NK cells /mm3 (%) | 638 (29) | 680 (66) | 1123 (73) | 1169 (68) | 60–434 (2–14) | 194–994 (3–14) | 182–1581 (3–13) |
| IgG (mg/dL) [Reference Range] | 220 [198–577] | 202 [165–781] | 316 [282–1026] | ||||
| IgM (mg/dL) [Reference Range] | 24 [16–100] | 34 [31–103] | 70 [39–142] | ||||
| IgA (mg/dL) [Reference Range] | <7 [1–52] | 7 [8–83] | 16 [16–83] | ||||
| Ab Responses: | |||||||
| Tetanus (IU/mL) (RR: 0.1–7) | 2.19 | 2.71 | |||||
| H. influenzae b (mcg/mL) (RR: 1.0–10.0) | 0.15 | 1.16 | |||||
| LPA responses: | |||||||
| Phytohemaglutinin (SI) [1:125] | 173 | 44 | 42 | ||||
| Pokeweed mitogen (SI) | 23 | 75 | 23 | ||||
| Tetanus antigen (SI) | 2 | 1 | |||||
| Candida antigen (SI) | 4 | 6 | |||||