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. 2015 Jan 9;35(2):125–134. doi: 10.1007/s10875-014-0123-3

Table 4.

Responses to questions regarding outcomes of pregnancies and management of common variable immune deficiency and hypogammaglobulinemia during pregnancy

Question First Pregnancy N = 385 Second Pregnancy N = 286 Third Pregnancy N = 153
How many years ago was this pregnancy? Average: 24.74 years Average: 27.42 years Average: 28.54 years
What was the outcome for this pregnancy? (ALL) Range: 0 to 63 years Range: 0 to 62 years Range: 1 to 59 years
Median: 24 years Median: 27 years Median: 28 years
N (%) N (%) N (%)
Live birth 270 (70) 222 (78) 103 (67)
Currently pregnant 6 (2) 2 (<1) 1 (<1)
Ectopic pregnancy 2 (1) 3 (1) 2 (1)
Spontaneous abortion/stillbirth 63 (16) 49 (17) 40 (26)
Terminated pregnancy 43 (11) 9 (3) 7 (5)
Did you go to an immunologist during this pregnancy? (diagnosed patients) N (%) N (%) N (%)
Yes 36 (69) 30 (70) 23 (72)
No 9 (17) 7 (16) 3 (9)
Did not have immunologist 7 (14) 6 (14) 6 (19)
Were you receiving IgG replacement therapy before this pregnancy? N (%) N (%) N (%)
Yes 42 (79) 35 (81) 25 (78)
No 11 (21) 18 (19) 7 (22)
Did you receive IgG replacement therapy during this pregnancy? N (%) N (%) N (%)
Yes 40 (77) 34 (79) 21 (66)
No 12 (23) 9 (21) 11 (34)
Did you continue your IgG replacement therapy during the entire pregnancy? N (%) N (%) N (%)
Yes 38 (95) 38 (95) 21 (100)
No 1 (3) 2 (5) 0 (0)
No answer 1 (3) 0 (0) 0 (0)
While you were pregnant did the number of grams of IgG increase, decrease or stay the same? N (%) N (%) N (%)
Increased 15 (40) 7 (18) 4 (19)
Decreased 1 (3) 0 (0) 0 (0)
Stayed the same 22 (58) 31 (82) 17 (81)
While pregnant did you receive IgG therapy more often, less often or did it stay the same? N (%) N (%) N (%)
More often 6 (16) 3 (8) 4 (19)
Less often 0 (0) 0 (0) 0 (0)
Stayed the same 32 (84) 35 (92) 17 (81)
Did you experience any serious side effect from your IgG therapy during this pregnancy? N (%) N (%) N (%)
Yes 3 (8) 2 (5) 2 (10)
No 35 (92) 35 (95) 19 (90)
Were there any changes to the PI testing you had done during your pregnancy? (Diagnosed only) N % N % N %
Yes 7 (14) 3 (7) 3 (10)
No 45 (86) 38 (93) 28 (90)