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. 2015 Jan 13;19(1):9. doi: 10.1186/s13054-014-0726-3

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© Ferrando et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Changes in the principal variables during the protocol. T₀: Baseline . T₁: 60, T₂: 120, T₃: 180 and T₄: 240 minutes after protocol defined ventilation was started. Data are presented as mean (SD). VT: tidal volume, Pplat: plateau pressure, RR: respiratory rate, PaCO₂: arterial partial pressure of CO₂, pH: acid-base state. *When significant difference (P <0.05) between Pplat-group versus SI-group.