Table 1.
Vaccination parameters weight gain, larvae counts and worm burden
| Animal ID | Weight gain [kg] | Larvae counts [LPG] * | Total worm count | Male worm count | Female worm count |
|---|---|---|---|---|---|
| Trial 1 | |||||
| Adjuvant only-control group | |||||
| 110 | 59 | 1047 | 1136 | 447 | 689 |
| 795 | 58 | 569 | 798 | 324 | 474 |
| 802 | 62 | 53 | 213 | 77 | 136 |
| 805 | 60 | 302 | 453 | 159 | 294 |
| 808 | 66 | 304 | 433 | 142 | 291 |
| 814 | 59 | 153 | 651 | 260 | 391 |
| Arithmetic mean | 61.7 | 404.7 | 614.0 | 234.8 | 379.2 |
| SDa | 2.9 | 359.8 | 324.7 | 136.3 | 189.4 |
| Geometric mean | 60.6 | 276.7 | 539.7 | 200.9 | 337.9 |
| SDg ** | 1.0 | 2.8 | 1.7 | 1.8 | 1.7 |
| rPMY group | |||||
| 806 | 69 | 609 | 925 | 351 | 574 |
| 812 | 49 | 131 | 4 | 1 | 3 |
| 813 | 76 | 7 | 64 | 21 | 43 |
| 822 | 70 | 116 | 126 | 60 | 66 |
| Arithmetic mean | 66.0 | 215.8 | 279.8 | 108.3 | 171.5 |
| SDa | 11.7 | 267.9 | 433.0 | 163.7 | 269.6 |
| Geometric mean | 65.1 | 92.2 | 77.6 | 30.2 | 50.0 |
| SDg ** | 1.2 | 5.0 | 7.0 | 8.5 | 6.5 |
| Reduction [%]*** | 46.7 (66.7) | 54.4 (85.6) | 53.9 (85.0) | 54.8 (85.2) | |
| Trial 2 | |||||
| GST-control group | |||||
| 361 | 22 | 67 | 940 | ||
| 129 | n.a. | 12 | 42 | ||
| 412 | 30 | 128 | 1101 | ||
| 269 | 53 | 84 | 873 | ||
| 553 | 18 | 201 | 1871 | ||
| Arithmetic mean | 30.8 | 98.4 | 965.4 | ||
| SDa | 15.6 | 70.8 | 652.0 | ||
| Geometric mean | 28.2 | 71.2 | 591.4 | ||
| SDg ** | 1.5 | 2.6 | 3.8 | ||
| rPMY group | |||||
| 699 | 39 | 87 | 1019 | ||
| 485 | 56 | 73 | 1192 | ||
| 034 | 70 | 25 | 917 | ||
| 906 | 76 | 0 | 0 | ||
| 887 | 23 | 26 | 209 | ||
| Arithmetic mean | 52.8 | 42.2 | 667.4 | ||
| SDa | 21.9 | 36.4 | 528.4 | ||
| Geometric mean | 48.6 | 20.5 | 187.0 | ||
| SDg ** | 1.1 | n.a. | n.a. | ||
| Reduction [%]*** | 57.1 (71.2) | 30.9 (68.4) | |||
| Dictol vaccine group | |||||
| 214 | 48 | 1 | 2 | ||
| 688 | 36 | 13 | 152 | ||
| 598 | 79 | 1 | 63 | ||
| 221 | 48 | 1 | 50 | ||
| 825 | 46 | 16 | 56 | ||
| Arithmetic mean | 51.4 | 6.4§ | 64.6 | ||
| SDa | 16.2 | 7.5 | 54.4 | ||
| Geometric mean | 49.7 | 3.5 | 37.6 | ||
| SDg ** | 1.1 | 1.5 | 1.6 | ||
| Reduction [%]*** | 93.5 (95.0) | 93.3 (93.6) | |||
SDa = arithmetic standard deviation, SDg = geometric standard deviation, n.a. = not available.
*Values represent the sum of fecal larvae counts from day 84 to 97.
**SDg is a multiplicative factor and therefore dimensionless.
***Percent reduction based on arithmetic mean with values in brackets representing percent reduction based on geometric mean.
§p ≤ 0.05.