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. 2015 Mar 4;14:15. doi: 10.1186/s12944-015-0013-6

Table 4.

Predicted ADME profiles for F18 bioactive compound and standard

Compound Aqueous Solubility Intensity Intestinal Absorption Intensity BBB Intensity PPB % of binding CYP450 Value Hepatotoxicity A logp 98 Hydrogen bond acceptor Hydrogen bond donor
F18 3 3 4 0 0 0 3.863 11 7
Atorvastatin 2 2 4 1 1 1 4.701 7 4