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. Author manuscript; available in PMC: 2015 Mar 7.
Published in final edited form as: Mol Biosyst. 2014 Oct 30;11(1):197–207. doi: 10.1039/c4mb00585f

Fig. 7.

Fig. 7

Impact of differentially regulated miRNAs on target binding. Transfection of miR-145 caused changes of other miRNAs that were assayed by miRNA microarrays. Through bioinformatics analysis, those upregulated miRNAs (red) were found to have target binding with lower TargetScan context scores (i.e. stronger binding to their targets). (A) Fold-change of miRNAs after miR-145 transfection. Only miRNAs targeting mRNA/protein pairs that showed concordant changes are depicted. (B) Upregulated miRNAs by miRNA-145 were predicted to possess stronger target binding than downregulated ones.