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. Author manuscript; available in PMC: 2015 Mar 7.
Published in final edited form as: Lancet Oncol. 2014 Mar 11;15(4):474–482. doi: 10.1016/S1470-2045(14)70035-X

Table 2.

Relative change of patients' bone mineral density from baseline

Exemestane
Anastrozole
p value*
N Mean % change (95% CI) N Mean % change (95% CI)
At 2 years
Hip
    Baseline T-score ≥−2.0 83 −1.93% (−2.93 to −0.93) 80 −2.71% (−4.32 to −1.11) 0.10
    Baseline T-score <−2.0 61 2.09% (−1.45 to 5.63) 55 0.00% (−3.67 to 3.66) 0.28
Lumbar spine
    Baseline T-score ≥−2.0 87 −0.92% (−2.35 to 0.50) 77 −2.39% (−3.77 to −1.01) 0.08
    Baseline T-score <−2.0 63 2.11% (−0.84 to 5.06) 57 3.72% (1.54 to 5.89) 0.26
At 1 year
Hip
    Baseline T-score ≥−2.0 99 −0.62% (−1.48 to 0.23) 114 −1.66% (−2.73 to −0.59) 0.01
    Baseline T-score <−2.0 64 0.61% (−1.81 to 3.04) 66 0.83% (−0.16 to 1.82) 0.23
Lumbar spine
    Baseline T-score ≥−2.0 102 −0.59% (−1.73 to 0.54) 116 −1.88% (−3.06 to −0.70) 0.32
    Baseline T-score <−2.0 69 3.75% (2.13 to 5.36) 66 2.60% (1.24 to 3.96) 0.67
*

Based on two-sided Student's t test of individual patient change.