Table 2.
Relative change of patients' bone mineral density from baseline
| Exemestane |
Anastrozole |
p value* | |||
|---|---|---|---|---|---|
| N | Mean % change (95% CI) | N | Mean % change (95% CI) | ||
| At 2 years | |||||
| Hip | |||||
| Baseline T-score ≥−2.0 | 83 | −1.93% (−2.93 to −0.93) | 80 | −2.71% (−4.32 to −1.11) | 0.10 |
| Baseline T-score <−2.0 | 61 | 2.09% (−1.45 to 5.63) | 55 | 0.00% (−3.67 to 3.66) | 0.28 |
| Lumbar spine | |||||
| Baseline T-score ≥−2.0 | 87 | −0.92% (−2.35 to 0.50) | 77 | −2.39% (−3.77 to −1.01) | 0.08 |
| Baseline T-score <−2.0 | 63 | 2.11% (−0.84 to 5.06) | 57 | 3.72% (1.54 to 5.89) | 0.26 |
| At 1 year | |||||
| Hip | |||||
| Baseline T-score ≥−2.0 | 99 | −0.62% (−1.48 to 0.23) | 114 | −1.66% (−2.73 to −0.59) | 0.01 |
| Baseline T-score <−2.0 | 64 | 0.61% (−1.81 to 3.04) | 66 | 0.83% (−0.16 to 1.82) | 0.23 |
| Lumbar spine | |||||
| Baseline T-score ≥−2.0 | 102 | −0.59% (−1.73 to 0.54) | 116 | −1.88% (−3.06 to −0.70) | 0.32 |
| Baseline T-score <−2.0 | 69 | 3.75% (2.13 to 5.36) | 66 | 2.60% (1.24 to 3.96) | 0.67 |
Based on two-sided Student's t test of individual patient change.